MTG6:
Hypothalamic and Pituitary Conditions

Existing guidelines

Bardet-Biedl syndrome 

Bardet-Biedl syndrome improved diagnosis criteria and management:  

Inter European Reference Networks consensus statement and recommendations 

Dollfus, H. Lilien, M.R., Maffei, P. et al 

European Journal of Human Genetics,  31 July 2024


Pituitary Adenomas

Read guideline on Acromegaly 
Laurence Katznelson, Edward R. Laws, Shlomo Melmed, Mark E. Molitch, Mohammad Hassan Murad, Andrea Utz & John A. H. Wass (1 November, 2014)
Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 11, Pages 3933–3951

Read guideline on Diagnosis and Treatment of Acromegaly 
Laurence Katznelson, John L. D. Atkinson, David M. Cook, FACE; Shereen Z. Ezzat, FRCPC; Amir H. Hamrahian, FACE; Karen K. Miller (2011)
Endocrine Practice, Volume 11, Supply 4

Read guideline on Diagnosis and Treatment of Hyperprolactinemia 
Shlomo Melmed, Felipe F. Casanueva, Andrew R. Hoffman, David L. Kleinberg, Victor M. Montori, Janet A. Schlechte & John A. H. Wass (1 February, 2011)
Journal of Clinical Endocrinology & Metabolism, Volume 96, Issue 2, Pages 273–288

Read guideline on Pituitary Incidentaloma 
Pamela U. Freda, Albert M. Beckers, Laurence Katznelson, Mark E. Molitch, Victor M. Montori, Kalmon D. Post & Mary Lee Vance (1 April, 2011)
Journal of Clinical Endocrinology & Metabolism, Volume 96, Issue 4, Pages 894–904,

Read guideline on Emergency Management of Pituitary Apoplexy in adult patients 
Baldeweg, S., Vanderpump, M., Drake, W., Reddy, N., Markey, A., Plant, G., Powell… Wass, J., & the Society for Endocrinology Clinical Committee (2016)
Endocrine Connections, 5(5), G12-G15.

Read guideline for the management of aggressive pituitary tumours and carcinomas 
Raverot, G., Burman, P., McCormack, A., Heaney, A., Petersenn, S., Popovic, V., Trouillas, J., Dekkers, O., & The European Society of Endocrinology (2018)
European Journal of Endocrinology, 178(1), G1-G24.

Read criteria on Pituitary Tumour Centers of Excellence: A Pituitary Society Statement 
Felipe F. Casanueva, Ariel L. Barkan, Michael Buchfelder, Anne Klibanski, Edward R. Laws, Jay S. Loeffler, Shlomo Melmed, & Andrea Giustina, On behalf of The Pituitary Society, Expert Group on Pituitary Tumors (2017)
Pituitary, 20:489–498 DOI 10.1007/s11102-017-0838-2

Read guideline on Multidisciplinary management of acromegaly: A consensus 
Andrea Giustina, Garni Barkhoudarian, Albert Beckers, Anat Ben-Shlomo, Nienke Biermasz, Beverly Biller,Cesar Boguszewski, Marek Bolanowski, Jens Bollerslev, Vivien Bonert, Marcello D. Bronstein, Michael Buchfelder, Felipe Casanueva, Philippe Chanson, David Clemmons, Maria Fleseriu, Anna Maria Formenti, Pamela Freda,Monica Gadelha,Eliza Geer, Mark Gurnell, Anthony P. Heaney, Ken K. Y. Ho, Adriana G. Ioachimescu, Steven Lamberts, Edward Laws, Marco Losa, Pietro Maffei,Adam Mamelak, Moises Mercado, Mark Molitch, Pietro Mortini, Alberto M. Pereira, Stephan Petersenn, Kalmon Post,Manuel Puig-Domingo,Roberto Salvatori, Susan L. Samson, Ilan Shimon,Christian Strasburger, Brooke Swearingen, Peter Trainer, Mary L. Vance, John Wass, Margaret E. Wierman, Kevin C. J. Yuen, Maria Chiara Zatelli, Shlomo Melmed
Springer (September 2020), DOI 10.1007/s11154-020-09588-z

Cushing’s Syndrome

Read guideline on the Diagnosis of Cushing’s Syndrome Lynnette K. Nieman, Beverly M. K. Biller, James W. Findling, John Newell-Price, Martin O. Savage, Paul M. Stewart, & Victor M. Montori (1 May, 2008)
Journal of Clinical Endocrinology & Metabolism, Volume 93, Issue 5, Pages 1526–1540

Read guideline on Treatment of Cushing’s Syndrome 
Lynnette K. Nieman, Beverly M. K. Biller, James W. Findling, M. Hassan Murad, John Newell-Price, Martin O. Savage & Antoine Tabarin (1 August, 2015)
Journal of Clinical Endocrinology & Metabolism, Volume 100, Issue 8, Pages 2807–2831

Acquired Hypopituitarism

Read guideline on Hormone Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Guideline 
Maria Fleseriu, Ibrahim A. Hashim, Niki Karavitaki, Shlomo Melmed, M. Hassan Murad, Roberto Salvatori & Mary H. Samuels ( 1 November, 2016)
Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, Pages 3888–3921

Read guideline for Growth Hormone use in Growth Hormone-deficient Adult and Transition Patients 
David M. Cook, FACE; Kevin C.J. Yuen, Beverly M.K. Biller, Stephen F. Kemp, FACE; & Mary Lee Vance (2009)
Endocrine Practice, Volume 15, Supply 2

Read guideline on Growth Hormone Treatment and risk of Solid Tumours 
Juul A, Bernasconi S, Carel J, -C, Clayton P, E, Kiess W & DeMuinck-Keizer Schrama S (2003)
Hormone Research, 60:103-104. doi: 10.1159/000071879

Consensus Statements

Congenital Hypopituitarism

Consensus guideline for the Diagnosis and Treatment of Growth Hormone (GH) Defiency in Childhood and Adolescence: Summary statement of the GH Research Society 
GH Research Society (2000). Journal of Clinical Endocrinology & Metabolism, Volume 85, No. 11

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