Endo-ERN Publications Database
940 publication(s) found matching the search criteria
The effect of coping strategies on health–related quality of life in acromegaly patients
Author(s):
Schock L, Chmielewski WX, Siegel S, Detomas M, Deutschbein T, Giese S, Honegger J, Unger N, Kreitschmann-Andermahr I
Affiliated Institution / ERN:
University Hospital Essen ; University Hospital Würzburg ; Universitätsklinikum Tübingen ;
Condition / Disease:
Acromegaly
Publication:
Endocrine v84.3 p1108-1115
Year:
2024
ORPHAcode / other:
ORPHA963
Venous thromboembolism in Cushing syndrome: results from an EuRRECa and Endo-ERN survey
Author(s):
Cherenko M, Appelman-Dijkstra NM, Priego Zurita AL, Biermasz NR, Dekkers OM, Klok FA, Reisch N, Aulinas A, Biagetti B, Cannavo S, Canu L, Detomas M, Devuyst F, Falhammar H, Feelders RA, Ferrau F, Gatto F, Grasselli C, van Houten P, Hoybye C, Isidori AM, Kyrilli A, Loli P, Maiter D, Nowak E, Pivonello R, Ragnarsson O, Steenaard RV, Unger N, van de Ven A, Webb SM, Yeste D, Ahmed SF, Pereira AM
Affiliated Institution / ERN:
Hôpital Universitaire de Bruxelles (HUDERF-Erasme) ; Amsterdam UMC ;
Condition / Disease:
Cushing disease
Publication:
Endocrine Connections v13.6
Year:
2024
ORPHAcode / other:
ORPHA96253
DOI:
10.1530/EC-24-0046
Keywords:
Cushing disease,Cushing syndrome,endogenous hypercortisolism,thromboprophylaxis,venous thromboembolism
Efficacy and tolerability of somatostatin analogues according to gender in patients with neuroendocrine tumors
Author(s):
Ruggeri RM, Aini I, Gay S, Grossrubatscher EM, Mancini C, Tarsitano MG, Zamponi V, Isidori AM, Colao A, Faggiano A
Affiliated Institution / ERN:
AOU Federico II - Naples ; AOU Policlinico Umberto I - Rome ; AOU polyclinic "G.Martino" of Messina ;
Condition / Disease:
Multiple endocrine neoplasia type 1
Publication:
Reviews in Endocrine and Metabolic Disorders v25.2 p383-398
Year:
2024
ORPHAcode / other:
ORPHA652
DOI:
10.1007/s11154-023-09858-6
Keywords:
Gender,Neuroendocrine neoplasms,PRRT,Somatostatin analogues (SSA),Somatostatin receptors (SSTR),Therapy
Classes and predictors of reversal in male patients with congenital hypogonadotropic hypogonadism: a cross-sectional study of six international referral centres
Author(s):
Dwyer AA, McDonald IR, Cangiano B, Giovanelli L, Maione L, Silveira LFG, Raivio T, Latronico AC, Young J, Quinton R, Bonomi M, Persani L, Seminara SB, Lee CS
Affiliated Institution / ERN:
IRCCS Auxologico Italian Institute - Milan ; Hôpital Bicêtre ; Helsinki University Hospital (HUS) ;
Condition / Disease:
Kallmann Syndrome
Publication:
The Lancet Diabetes & Endocrinology v12.4 p257-266
Year:
2024
ORPHAcode / other:
ORPHA478
A European Network for the Investigation of Gender Incongruence in adolescents
Author(s):
Boogers LS, Wiepjes CM, Staphorsius AS, Klink DT, Ciancia S, Romani A, Stolk THR, van den Boogaard E, Steensma TD, de Vries ALC, van Trotsenburg ASP, den Heijer M, Fisher AD, Cools M, Hannema SE
Affiliated Institution / ERN:
Ghent University Hospital ; University Hospital Florence ; Amsterdam UMC ;
Condition / Disease:
Transgender, female to male
Publication:
The Journal of Sexual Medicine v21.4 p350-356
Year:
2024
ORPHAcode / other:
ICD-10 F64
DOI:
10.1093/jsxmed/qdae014
Keywords:
GAH,GnRHa,adolescent,estradiol,puberty,testosterone,transgender
Exploring sexual function in adrenal insufficiency: findings from the Dual RElease hydrocortisone versus conventionAl glucocorticoid replaceMent therapy in hypocortisolism (DREAM) trial
Author(s):
Hasenmajer V, De Alcubierre D, Ferrari D, Minnetti M, Bonaventura I, Pofi R, Simeoli C, Tomaselli A, Sciarra F, Bottillo G, Angelini F, Cozzolino A, Venneri MA, Jannini EA, Gianfrilli D, Pivonello R, Isidori AM
Affiliated Institution / ERN:
AOU Federico II - Naples ; AOU Policlinico Umberto I - Rome ;
Condition / Disease:
Chronic adrenocorticoid insufficiency
Publication:
Andrology doi:10.1111/andr.13635
Year:
2024
ORPHAcode / other:
ORPHA101959
DOI:
10.1111/andr.13635
Keywords:
adrenal insufficiency,dual‐release hydrocortisone,erectile dysfunction,sexual function
Increased risk of nephrolithiasis: an emerging issue in children with congenital adrenal hyperplasia due to 21-hydroxylase deficiency
Author(s):
Chiarito M, Lattanzio C, D’Ascanio V, Capalbo D, Cavarzere P, Grandone A, Aiello F, Pepe G, Wasniewska M, Zoller T, Salerno M, Faienza MF
Affiliated Institution / ERN:
AOU Federico II - Naples ; AOUI Verona ; AOU polyclinic "G.Martino" of Messina ; AOU University of Campania "Luigi Vanvitelli", Naples ;
Condition / Disease:
Congenital Adrenal Hyperplasia
Publication:
Endocrine v84.2 p727-734
Year:
2024
ORPHAcode / other:
ORPHA418
DOI:
10.1007/s12020-024-03792-6
Keywords:
17-OHP,21-hydroxylase deficiency (21-OHD),ACTH,Congenital adrenal hyperplasia (CAH),Nephrolithiasis
IGF‐1 as screening tool for acromegaly and adult‐onset growth hormone deficiency in the Netherlands
Author(s):
Postma MR, van Beek AP, van der Klauw MM, Lentjes EGWM, Muller Kobold AC
Affiliated Institution / ERN:
University Medical Center Groningen ;
Condition / Disease:
Pituitary
Publication:
Clinical Endocrinology v100.3 p260-268
Year:
2024
ORPHAcode / other:
ORPHA963; ORPHA95502;
Changes in depression symptom profile with gender-affirming hormone use in transgender persons
Author(s):
Morssinkhof MW, Wiepjes CM, van den Heuvel OA, Kreukels BP, van der Tuuk K, T'Sjoen G, den Heijer M, Broekman BF
Affiliated Institution / ERN:
Ghent University Hospital ; Amsterdam UMC ; University Medical Center Groningen ;
Condition / Disease:
Transgender, female to male
Publication:
Journal of Affective Disorders v348 p323-332
Year:
2024
ORPHAcode / other:
ICD-10 F64
DOI:
10.1016/j.jad.2023.12.056
Keywords:
Depression,Estrogen,Gender affirming hormone therapy,Testosterone,Transgender
Sunitinib for metastatic progressive phaeochromocytomas and paragangliomas: results from FIRSTMAPPP, an academic, multicentre, international, randomised, placebo-controlled, double-blind, phase 2 trial
Author(s):
Baudin E, Goichot B, Berruti A, Hadoux J, Moalla S, Laboureau S, Nölting S, de la Fouchardière C, Kienitz T, Deutschbein T, Zovato S, Amar L, Haissaguerre M, Timmers H, Niccoli P, Faggiano A, Angokai M, Lamartina L, Luca F, Cosentini D, Hahner S, Beuschlein F, Attard M, Texier M, Fassnacht M, DOCAO C, Drui D, Borson Chazot F, Chabre O, Vezzosi D, Castinetti F, Bertherat J, Libé R, Gimenez-Roqueplo AP, Favier J, Quinkler M, Strasburger C, Zopf K, Reincke M, Kroiss M, Remde H, Haaf M, Fuß CT, Dischinger U, Eisenhofer G, Pamporaki C, Van Berkel A
Affiliated Institution / ERN:
Radboud University Medical Centre Nijmegen ; Assistance Publique-Hôpitaux de Paris, Hôpital Cochin ;
Condition / Disease:
Sporadic phaeochromocytoma/secreting paraganglioma
Publication:
The Lancet v403.10431 p1061-1070
Year:
2024
ORPHAcode / other:
ORPHA276621
IGF‐1 as screening tool for acromegaly and adult‐onset growth hormone deficiency in the Netherlands
Author(s):
Postma MR, van Beek AP, van der Klauw MM, Lentjes EGWM, Muller Kobold AC
Affiliated Institution / ERN:
University Medical Center Groningen ; University Medical Center Utrecht ;
Condition / Disease:
Pituitary gigantism
Publication:
Clinical Endocrinology v100.3 p260-268
Year:
2024
ORPHAcode / other:
ORPHA99725
Hypophosphatasia diagnosis: current state of the art and proposed diagnostic criteria for children and adults
Author(s):
Khan AA, Brandi ML, Rush ET, Ali DS, Al-Alwani H, Almonaei K, Alsarraf F, Bacrot S, Dahir KM, Dandurand K, Deal C, Ferrari SL, Giusti F, Guyatt G, Hatcher E, Ing SW, Javaid MK, Khan S, Kocijan R, Linglart A, M’Hiri I, Marini F, Nunes ME, Rockman-Greenberg C, Roux C, Seefried L, Simmons JH, Starling SR, Ward LM, Yao L, Brignardello-Petersen R, Lewiecki EM
Affiliated Institution / ERN:
Hôpital Bicêtre ;
Condition / Disease:
Hypophosphatasia
Publication:
Osteoporosis International v35.3 p431-438
Year:
2024
ORPHAcode / other:
ORPHA436
Near Adult Height and Body Mass Index Changes in Growth Hormone Treated Short Children with Noonan Syndrome: The Belgian Experience
Author(s):
De Schepper J, Thomas M, Huysentruyt K, Becker M, Boros E, Casteels K, Chivu O, De Waele K, Dotremont H, Lysy PA, Massa G, Parent A, Rochtus A, Gies I
Affiliated Institution / ERN:
Hôpital Universitaire de Bruxelles (HUDERF-Erasme) ; UZ Brussels ; University Hospitals Saint-Luc ; University Hospital Liège ; Ghent University Hospital ; UZ Antwerpen ; UZ Leuven ;
Condition / Disease:
Noonan Syndrome
Publication:
Hormone Research in Paediatrics p1-13
Year:
2024
ORPHAcode / other:
ORPHA648
The challenge of hypophosphatasia diagnosis in adults: results from the HPP International Working Group Literature Surveillance
Author(s):
Brandi ML, Khan AA, Rush ET, Ali DS, Al-Alwani H, Almonaei K, Alsarraf F, Bacrot S, Dahir KM, Dandurand K, Deal C, Ferrari SL, Giusti F, Guyatt G, Hatcher E, Ing SW, Javaid MK, Khan S, Kocijan R, Lewiecki EM, Linglart A, M’Hiri I, Marini F, Nunes ME, Rockman-Greenberg C, Seefried L, Simmons JH, Starling SR, Ward LM, Yao L, Brignardello-Petersen R, Roux C
Affiliated Institution / ERN:
Hôpital Bicêtre ;
Condition / Disease:
Hypophosphatasia
Publication:
Osteoporosis International v35.3 p439-449
Year:
2024
ORPHAcode / other:
ORPHA436
DOI:
10.1007/s00198-023-06859-8
Keywords:
Diagnostic parameters,HPP diagnosis in adults,Hypophosphatasia,Systematic review
Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS)
Author(s):
Hendricks LAJ, Verbeek KCJ, Schuurs-Hoeijmakers JHM, Mensenkamp AR, Brems H, de Putter R, Anastasiadou VC, Villy M, Jahn A, Steinke-Lange V, Baldassarri M, Irmejs A, de Jong MM, Links TP, Leter EM, Bosch DGM, Høberg-Vetti H, Tveit Haavind M, Jørgensen K, Mæhle L, Blatnik A, Brunet J, Darder E, Tham E, Hoogerbrugge N, Vos JR
Affiliated Institution / ERN:
University Medical Center Groningen ; UZ Leuven ;
Condition / Disease:
Partial gonadal dysgenesis
Publication:
Cancers v16.5 p953
Year:
2024
ORPHAcode / other:
NO XX CODE
DOI:
10.3390/cancers16050953
Keywords:
alcohol drinking,body mass index,breast neoplasm,exercise,hamartoma syndrome,multiple
Transition from pediatric to adult care in patients with Turner syndrome in Italy: a consensus statement by the TRAMITI project
Author(s):
Aversa T, De Sanctis L, Faienza MF, Gambineri A, Balducci A, D’Aprile R, Di Somma C, Giavoli C, Grossi A, Meriggiola MC, Profka E, Salerno M, Stagi S, Scarano E, Zatelli MC, Wasniewska M
Affiliated Institution / ERN:
Foundation IRCCS CA'Granda Ospedale Maggiore polyclinic - Milan ; AOU polyclinic "G.Martino" of Messina ; AO City of Health and Science - Turin ; University Hospital of Padova ; AOU-Bologna ; AOU Federico II - Naples ; University Hospital Florence ; Meyer Children’s Hospital Florence ; AOU - Ferrara ;
Condition / Disease:
Other
Publication:
Journal of Endocrinological Investigation v47.7 p1585-1598
Year:
2024
ORPHAcode / other:
ORPHA325546
Multi-Stakeholder Opinion Statement on the Care of Individuals Born with Differences of Sex Development: Common Ground and Opportunities for Improvement
Author(s):
Cools M, Cheng EY, Hall J, Alderson J, Amies Oelschlager A, Balen AH, Chan Y, Geffner ME, Gravholt CH, Güran T, Hoebeke P, Lee P, Magritte E, Matos D, McElreavey K, Meyer-Bahlburg HF, Rink RC, Springer A, Szymanski KM, Vilain E, Williams J, Wolffenbuttel KP, Sandberg DE, Subramaniam R
Affiliated Institution / ERN:
Aarhus University Hospital ;
Condition / Disease:
DSD
Publication:
Hormone Research in Paediatrics p1-17
Year:
2024
ORPHAcode / other:
ORPHA98085; ORPHA2982; ORPHA325546
Multi-Stakeholder Opinion Statement on the Care of Individuals Born with Differences of Sex Development: Common Ground and Opportunities for Improvement
Author(s):
Cools M, Cheng EY, Hall J, Alderson J, Amies Oelschlager A, Balen AH, Chan Y, Geffner ME, Gravholt CH, Güran T, Hoebeke P, Lee P, Magritte E, Matos D, McElreavey K, Meyer-Bahlburg HF, Rink RC, Springer A, Szymanski KM, Vilain E, Williams J, Wolffenbuttel KP, Sandberg DE, Subramaniam R
Affiliated Institution / ERN:
Ghent University Hospital ; Erasmus MC: University Medical Center Rotterdam ; Aarhus University Hospital ;
Condition / Disease:
Other
Publication:
Hormone Research in Paediatrics p1-17
Year:
2024
ORPHAcode / other:
ORPHA98085
Consensus conference statement on fluorescence-guided surgery (FGS) ESSO course on fluorescence-guided surgery
Author(s):
van Dam M, Bijlstra O, Faber R, Warmerdam M, Achiam M, Boni L, Cahill R, Chand M, Diana M, Gioux S, Kruijff S, Van der Vorst J, Rosenthal R, Polom K, Vahrmeijer A, Mieog J
Affiliated Institution / ERN:
University Medical Center Groningen ; Maria Sklodowska-Curie National Research Institute of Oncology (MSCNRIO) ;
Condition / Disease:
Follicular thyroid carcinoma
Publication:
European Journal of Surgical Oncology v50.2 p107317
Year:
2024
ORPHAcode / other:
ORPHA146
Idiopathic isolated adrenocorticotropic hormone deficiency: a systematic review of a heterogeneous and underreported disease
Author(s):
Van Mieghem E, De Block C, De Herdt C
Affiliated Institution / ERN:
UZ Antwerpen ;
Condition / Disease:
Acquired pituitary hormone deficiency
Publication:
Pituitary v27.1 p23-32
Year:
2024
ORPHAcode / other:
ORPHA95502
DOI:
10.1007/s11102-023-01366-9
Keywords:
Acquired,Adrenal insufficiency,Anti-pituitary antibody,Hypopituitarism,Idiopathic isolated ACTH deficiency
Pituitary: hic manebimus optime
Author(s):
Giustina A
Affiliated Institution / ERN:
San Raffaele hospital - Milan ;
Condition / Disease:
Pituitary adenoma
Publication:
Pituitary v27.1 p3-6
Year:
2024
ORPHAcode / other:
ORPHA99408
Presentation of Graves’ orbitopathy within European Group On Graves’ Orbitopathy (EUGOGO) centres from 2012 to 2019 (PREGO III)
Author(s):
Schuh A, Ayvaz G, Baldeschi L, Baretić M, Bechtold D, Boschi A, Brix TH, Burlacu M, Ciric J, Covelli D, Currò N, Donati S, Eckstein AK, Fichter N, Führer D, Horn M, Jabłońska-Pawlak A, Juri Mandić J, Kahaly GJ, Konuk O, Langbein A, Lanzolla G, Marcocci C, Marinò M, Miśkiewicz P, Beleslin BN, Pérez-Lázaro A, Pérez-López M, Ponto KA, Quinn A, Rudofsky G, Salvi M, Schittkowski MP, Tanda ML, Toruner F, Vaidya B, Hintschich CR
Affiliated Institution / ERN:
University Hospital Essen ;
Condition / Disease:
Graves' orbitopathy
Publication:
British Journal of Ophthalmology v108.2 p294-300
Year:
2024
ORPHAcode / other:
ORPHA466682
Correction: consensus on criteria for acromegaly diagnosis and remission
Author(s):
Giustina A, Biermasz N, Casanueva FF, Fleseriu M, Mortini P, Strasburger C, van der Lely AJ, Wass J, Melmed S
Affiliated Institution / ERN:
San Raffaele hospital - Milan ; Leiden University Medical Center ;
Condition / Disease:
Acromegaly
Publication:
Pituitary v27.1 p88-88
Year:
2024
ORPHAcode / other:
ORPHA963
Congenital Hyperinsulinism in Humans and Insulin Secretory Dysfunction in Mice Caused by Biallelic DNAJC3 Variants
Author(s):
Welters A, Nortmann O, Wörmeyer L, Freiberg C, Eberhard D, Bachmann N, Bergmann C, Mayatepek E, Meissner T, Kummer S
Affiliated Institution / ERN:
Universitätsklinikum Düsseldorf ;
Condition / Disease:
Diazoxide-sensitive diffuse hyperinsulinism
Publication:
International Journal of Molecular Sciences v25.2 p1270
Year:
2024
ORPHAcode / other:
ORPHA165985
DOI:
10.3390/ijms25021270
Keywords:
BiP/GRP78 co-chaperone,calcium leak,endoplasmic reticulum stress,hyperinsulinemic hypoglycemia,intracellular calcium homeostasis,monogenic diabetes
Semen quality and metabolic profile in people with type 1 diabetes with and without erectile dysfunction: a cross-sectional study
Author(s):
Longo M, Caruso P, Varro C, Tomasuolo M, Cirillo P, Scappaticcio L, Romano L, Arcaniolo D, Maiorino MI, Bellastella G, De Sio M, Esposito K
Affiliated Institution / ERN:
AOU University of Campania "Luigi Vanvitelli", Naples ;
Condition / Disease:
diabetes type 1
Publication:
Journal of Endocrinological Investigation v47.7 p1787-1795
Year:
2024
ORPHAcode / other:
Disease control of acromegaly does not prevent excess mortality in the long term: results of a nationwide survey in Italy
Author(s):
Arosio M, Sciannameo V, Contarino A, Berchialla P, Puglisi S, Pesatori AC, Ferrante E, Filopanti M, Pivonello R, Dassie F, Rochira V, Cannavò S, De Menis E, Pigliaru F, Grottoli S, Cambria V, Faustini-Fustini M, Montini M, Peri A, Ceccato F, Puxeddu E, Borretta G, Bondanelli M, Ferone D, Colao A, Terzolo M, Reimondo G
Affiliated Institution / ERN:
AOU Federico II - Naples ; AOU - Modena ; University Hospital of Padova ; IRCCS Ospedale Policlinico San Martino – Genova ; AO City of Health and Science - Turin ; AOU polyclinic "G.Martino" of Messina ;
Condition / Disease:
Acromegaly
Publication:
Journal of Endocrinological Investigation v47.6 p1457-1465
Year:
2024
ORPHAcode / other:
ORPHA963
Factors associated with disease control failure in acromegaly patients treated with pegvisomant: an ACROSTUDY analysis
Author(s):
Giampietro A, Chiloiro S, Urbani C, Pivonello R, Carlsson MO, Dassie F, Prencipe N, Ragonese M, Gomez R, Granato S, Cannavò S, Grottoli S, Maffei P, Colao A, Bogazzi F, Bianchi A
Affiliated Institution / ERN:
AOU Federico II - Naples ; University Hospital of Padova ; AOU Pisan ; AO City of Health and Science - Turin ;
Condition / Disease:
Acromegaly
Publication:
Endocrine Connections v13.3
Year:
2024
ORPHAcode / other:
ORPHA963
The economic burden of pediatric growth hormone deficiency in Italy: a cost of illness study
Author(s):
Cappa M, Pozzobon G, Orso M, Maghnie M, Patti G, Spandonaro F, Granato S, Novelli G, La Torre D, Salerno M, Polistena B
Affiliated Institution / ERN:
San Raffaele hospital - Milan ;
Condition / Disease:
growth hormone deficiency
Publication:
Journal of Endocrinological Investigation v47.7 p1743-1750
Year:
2024
ORPHAcode / other:
ORPHA631; ORPHA101957;
DOI:
10.1007/s40618-023-02277-z
Keywords:
Children,Cost of illness,Economic burden,Growth hormone deficiency,Italy
A pharmacoeconomic analysis from Italian guidelines for the management of prolactinomas
Author(s):
Basile M, Valentini I, Attanasio R, Cozzi R, Persichetti A, Samperi I, Scoppola A, Auriemma RS, Menis ED, Esposito F, Ferrante E, Iatì G, Mazzatenta D, Maurizio Poggi, Rudà R, Tortora F, Cruciani F, Mitrova Z, Saulle R, Vecchi S, Cappabianca P, Paoletta A, Bozzao A, Caputo M, Doglietto F, Ferraù F, Lania AG, Laureti S, Lello S, Locatelli D, Maffei P, Minniti G, Peri A, Ruini C, Settanni F, Silvani A, Veronese N, Grimaldi F, Papini E, Cicchetti A
Affiliated Institution / ERN:
Foundation IRCCS CA'Granda Ospedale Maggiore polyclinic - Milan ; AOU Federico II - Naples ; AO City of Health and Science - Turin ; University Hospital of Padova ; University Hospital Florence ; AOU-Bologna ;
Condition / Disease:
Prolactinoma
Publication:
Global and Regional Health Technology Assessment v11.1 p1-16
Year:
2024
ORPHAcode / other:
ORPHA2965
Epidemiology of gastroenteropancreatic neuroendocrine neoplasms: a review and protocol presentation for bridging tumor registry data with the Italian association for neuroendocrine tumors (Itanet) national database
Author(s):
Panzuto F, Partelli S, Campana D, de Braud F, Spada F, Cives M, Tafuto S, Bertuzzi A, Gelsomino F, Bergamo F, Marcucci S, Mastrangelo L, Massironi S, Appetecchia M, Filice A, Badalamenti G, Bartolomei M, Amoroso V, Landoni L, Rodriquenz MG, Valente M, Colao A, Isidori A, Fanciulli G, Bollina R, Ciola M, Butturini G, Marconcini R, Arvat E, Cinieri S, Berardi R, Baldari S, Riccardi F, Spoto C, Giuffrida D, Gattuso D, Ferone D, Rinzivillo M, Bertani E, Versari A, Zerbi A, Lamberti G, Lauricella E, Pusceddu S, Fazio N, Dell’Unto E, Marini M, Falconi M
Affiliated Institution / ERN:
AOU Federico II - Naples ; AOU Policlinico Umberto I - Rome ; IRCCS Ospedale Policlinico San Martino – Genova ; AO City of Health and Science - Turin ;
Condition / Disease:
Multiple endocrine neoplasia type 1
Publication:
Endocrine v84.1 p42-47
Year:
2024
ORPHAcode / other:
ORPHA652
DOI:
10.1007/s12020-023-03649-4
Keywords:
Neuroendocrine tumors,database.,epidemiology,management,registry