Novel model to study the physiological effects of temporary or prolonged sex steroid deficiency in male mice

We developed a rodent model of chemical castration, which can be used as an alternative to surgical castration. Moreover, the transient nature of the intervention enables to study the effects of delayed puberty and reversibility of sex steroid deficiency.

Overview publication

TitleNovel model to study the physiological effects of temporary or prolonged sex steroid deficiency in male mice
DateMarch 1st, 2021
Issue nameAmerican Journal of Physiology-Endocrinology and Metabolism
Issue numberv320.3 pE415-E424
DOI10.1152/ajpendo.00401.2020
AuthorsKim NR, Khalil R, David K, Antonio L, Schollaert D, Deboel L, Van Herck E, Wardenier N, Cools M, Decallonne B, Claessens F, Dubois V & Vanderschueren D
MTGsMTG7
Read Read publication