Acromegaly: An Endocrine Society Clinical Practice Guideline


The aim was to formulate clinical practice guidelines for acromegaly.


The Task Force included a chair selected by the Endocrine Society Clinical Guidelines Subcommittee (CGS), five experts in the field, and a methodologist. The authors received no corporate funding or remuneration. This guideline is cosponsored by the European Society of Endocrinology.


This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence. The Task Force reviewed primary evidence and commissioned two additional systematic reviews.

Consensus Process

One group meeting, several conference calls, and e-mail communications enabled consensus. Committees and members of the Endocrine Society and the European Society of Endocrinology reviewed drafts of the guidelines.


Using an evidence-based approach, this acromegaly guideline addresses important clinical issues regarding the evaluation and management of acromegaly, including the appropriate biochemical assessment, a therapeutic algorithm, including use of medical monotherapy or combination therapy, and management during pregnancy.

Overview publication

TitluAcromegaly: An Endocrine Society Clinical Practice Guideline
Dată1 noiembrie 2014
Nume emitereThe Journal of Clinical Endocrinology & Metabolism
Număr emitereVolume 99, Issue 11, 1 November 2014, Pages 3933–3951
AutoriLaurence Katznelson, Edward R Laws, Jr, Shlomo Melmed, Mark E Molitch, Mohammad Hassan Murad, Andrea Utz & John A H Wass
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