Universitätsklinikum Münster

The Centre for Reproductive Medicine and Andrology (CeRA) as part of the University Hospital Münster, Germany, is a Centre of Excellence for clinical research and clinical services in Andrology and Reproduction.

CeRA consists of the Institute of Reproductive and Regenerative Biology and the De-partment of Clinical and Operative Andrology. The latter closely collaborates with the Unit for Assisted Reproduction as part of the Department of Gynaecology and Obstet-rics.
Basic scientists and physicians combine their multi-disciplinary expertise in reproduc-tive biology and reproductive clinical care.

Research in CeRA focuses on important issues of male reproductive biology and their potential clinical applications.
One specific focus of its basic research is the elucidation of genetic control and mainte-nance of human spermatogenesis. A further major topic is the ex-vivo generation of elongated spermatids from spermatogonial stem cells.

Regarding clinical research, fertility aspects in the care and treatment of Differences in Sex Development and maturation (DSD) such as:
● Klinefelter syndrome or other sex chromosomal aneuploidies,
● 46, XY DSD,
● 46, XY congenital adrenal hyperplasia (CAH) and
● 46, XY congenital hypogonadotropic hypogonadism (CHH)
● Congenital multiple pituitary hormone deficiencies (MHPD)

are in the specific focus of interest.

Observational clinical studies are conducted to better describe and understand these and other male fertility disorders, and to elaborate novel treatments. In addition, strat-egies for surgical retrieval and cryopreservation of spermatozoa were established.
Clinical issues are addressed in collaboration with the Department of Pediatric Endo-crinology and the Department of Endocrinology of the University Hospital Münster

Universitätsklinikum Münster is participating in the following Main Thematic Groups (MTGs):

• MTG7Sex Development & Maturation

General representatives