Genetic Disorders of Glucose & Insulin Homeostasis

Genetic disorders of Glucose & Insulin Homeostasis

For genetic disorders of glucose and insulin homeostasis 3 subthematic subgroups are defined:

  • Insulin-resistance syndrome,
  • Hyperinsulinism and other forms of hypoglycemia
  • Rare diabetes mellitus

    All guidelines for disorders of insulin and glucose homeostasis recommend education in glucose monitoring, diet and pharmacologic treatment with insulin and/or other medication during paediatric long-term care. The purpose of our network is to provide modern, evidence-based care through a multidisciplinary approach to children and adolescents suffering from a rare form of diabetes, hyperinsulinism or lipodystrophy. These include patients with an exceptional cause of diabetes (e.g. insulin-receptor mutations) , patients with severely unstable and/or difficult to treat diabetes (e.g. neonatal diabetes), patients with uncommon comorbidities (e.g. WABB syndromes).